Brendan O’Brien, MD

Brendan O'Brien

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Brendan O’Brien, M.D., is a board-certified otolaryngologist – head and neck surgeon. Dr. O’Brien received his Bachelor of Science in Biochemistry at the University of Buffalo and graduated cum laude. He completed his medical school at Stony Brook University in 2009. He was a recipient of the Glorney-Raisbeck Medical Student Grant in Cardiovascular Research and made the National Dean’s List.

Dr. O’Brien completed his internship and residency training in the Department of Otolaryngology – Head and Neck Surgery at the University of Rochester in 2014. He stayed on as a faculty member at the university to train other residents and promote education. He successfully established two practices to expand the footprint of the department during his three-year faculty position. Prior to joining Advanced ENT & Allergy, he held a faculty position at Thomas Jefferson University in the Department of Otolaryngology – Head and Neck Surgery.

Dr. O’Brien is an active member of the American Academy of Otolaryngology – Head and Neck Surgery and has authored multiple peer reviewed publications. He provides services in all facets of otolaryngology and has a particular interest in rhinosinusitis.

Dr. O’Brien lives in Philadelphia with his wife Marlene, a vascular surgeon who practices in New Jersey. In their free time, the pair enjoy traveling and spending time outdoors. Dr. O’Brien is also a native of Buffalo, New York and passionate Bills fan; sorry, E-A-G-L-E-S!

Office Locations

Accepting New Patients

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Medical Education

Stony Brook University School of Medicine, Stony Brook, NY


University of Rochester, Rochester, NY

Board Certifications

American Academy of Otolaryngology – Head and Neck Surgery

Clinical Instructor

Thomas Jefferson University Hospital, Philadelphia, PA